Abstract We evaluate the shared genetic regulation of mRNA molecules, proteins and metabolites derived from whole blood from 3029 human donors.We find abundant allelic heterogeneity, where multiple variants regulate a particular molecular phenotype, and pleiotropy, where a single variant associates with multiple molecular phenotypes over multiple g

In recent years, various types of surrogate optimization models have been proposed to reduce the computational time and to improve the emulation accuracy.In this study, by leveraging an ANN surrogate model developed earlier, a comprehensive and efficient optimization algorithm is conceived for the aluminum lotion global optimal design of an integra

Endocardiosis is a disease commonly found in Pomeranian dog characterized by progressive myxomatousdegeneration of the atrio-ventricular valves especially in the mitral valve.The purpose of this study was todefine the diagnose and severeity of this disease on the Pomeranian by using brightness mode, motion mode,dan color flow Doppler echocardiograp

The popularity of Commercial Electric Vehicles (CEVs) has experienced a surge in recent years, particularly in urban vocational contexts, as a means of advancing towards the goal of attaining net-zero emissions by 2050.The return-to-base charging strategy, which involves charging CEVs at depots, has become a prevalent practice for smaller CEV fleet

INTRODUCTION: To evaluate the performance of first trimester nuchal translucency scan screening among pregnant women in Nigeria.Methods: A prospective observational and questionnaire based study involving 510 pregnant women between 11+0 and 13+6 weeks.Routine counselling and nuchal translucency measurement was conducted using the FMF, London guidel